Hidroxipropil metilcelulosa (HPMC) Venta al por mayor

Hydroxypropyl Methylcellulose (HPMC) Uses

Hydroxypropyl Methylcellulose (HPMC) is mainly derived from refined cotton/wood pulp, which is alkalized to obtain cellulose, and then added with propylene oxide and methyl chloride for etherification to obtain cellulose ether.

HPMC Cellulose act as thickener, water retaining agent, dispersant, stabilizer, emulsifier, binder, excipient, film former in various industries. HPM cellulose is widely used in construction dry-mixed mortar, pharmaceutical, petrochemical, ceramics, paper, synthetic resin, leather, food and cosmetics and other industries.

KimaCell® Hydroxypropyl Methylcellulose (HPMC) has the advantages of wide application, small unit usage, good modification effect, and environmental friendliness. HPMC products can significantly improve and optimize product performance in the field of its addition, which is conducive to improving resource utilization efficiency and product added value. Environmentally friendly additives that are essential in various fields.

1. HPMC In Pharmaceutical

In the field of medicine, Hydroxypropyl Methylcellulose (HPMC) is an important pharmaceutical excipient, which can be used in drug sustained and controlled release preparations, vegetable capsules, tablet coatings, suspending agents, tablet binders, tablet disintegrants and other application scenarios.

2. Hydroxypropyl Methyl Cellulose In Food

Food grade Hydroxypropyl Methylcellulose (HPMC) is a recognized safe food additive. It can be used as a food thickener, stabilizer and moisturizer to thicken, retain water, and improve taste. It is widely used in developed countries, mainly for baked food, collagen Protein casings, whipped cream, fruit juices, sauces, meat and other protein products, fried foods, etc. China, the United States, the European Union, and many other countries allow HPMC to be used as a food additive.

The proportion of food-grade Hydroxypropyl Methylcellulose (HPMC) used in food production in China is relatively low. The domestic market is still in the stage of application and promotion, coupled with the high price of food-grade HPMC, HPMC is used in fewer fields in food production in my country. However, with the improvement of income, the scale of the food industry is expected to maintain steady growth in the long run. Moreover, with the improvement of people's awareness of healthy food, the penetration rate of HPMC as a health additive will gradually increase. The consumption of HPMC in the food industry expected to grow further.

3. HPMC For Construction

In Construction drymix mortar industry, Hydroxypropyl Methylcellulose is used as a water-retaining agent and retarder for cement mortar to make the mortar pumpable. HPMC Used as a binder in plaster, plaster, putty powder or other building materials to improve spreadability and prolong work time. HPMC can be used as paste tile, marble, plastic decoration, paste reinforcement, and can also reduce the amount of cement. The water-retaining performance of HPMC prevents the slurry from cracking due to drying too quickly after application, and enhances the strength after hardening.

Hydroxypropyl Methylcellulose Benefits

Hydroxypropyl methylcellulose (HPMC) offers a wide range of benefits across different industries. HPMC versatile nature as thickener, stabilizer, film-former, and water-retaining agent makes it an indispensable ingredient in pharmaceuticals, food products, cosmetics, and construction materials. Whether it's providing controlled drug release in pharmaceutical formulations, improving texture and stability in food products, enhancing the performance of cosmetic formulations, or optimizing the properties of construction materials, HPMC plays a vital role.HPMC offers numerous benefits due to its unique properties, making it a valuable ingredient in many products.

• Pharmaceutical Benefits:

a. Controlled Drug Release: HPMC is commonly used as a matrix former in oral solid dosage forms, such as tablets and capsules. It provides controlled drug release, ensuring a steady and sustained release of the active pharmaceutical ingredient (API) over an extended period. This feature is particularly beneficial for drugs that require a slow release pattern to maintain therapeutic efficacy.

b. Film Coating: HPMC forms a uniform and smooth film when applied to tablets or capsules, offering protection against environmental factors such as moisture, light, and air. It also improves the appearance, swallowability, and stability of the dosage form.

c. Mucoadhesive Properties: HPMC can adhere to the mucosal surfaces, enhancing the contact time and improving drug absorption. This property is useful in the development of various oral and ocular drug delivery systems.

• Food Benefits:

a. Thickening and Stabilization: HPMC acts as a thickening and stabilizing agent in food products. It imparts viscosity, texture, and creaminess to sauces, dressings, and dairy products. It prevents phase separation and maintains the homogeneity of food formulations.

b. Fat Replacement: HPMC can be used as a fat replacer in low-fat food products. It mimics the mouthfeel and texture of fats, providing a desirable sensory experience while reducing the calorie content.

c. Water Retention: HPMC has the ability to retain water, thereby preventing moisture loss and maintaining the juiciness and freshness of food products. It is particularly useful in baked goods, where it improves shelf life and texture.

• Cosmetics Benefits:

a. Thickening and Emulsifying Agent: HPMC cellulose is widely used in cosmetic formulations, such as creams, lotions, and shampoos, due to its excellent thickening and emulsifying properties. It improves the stability and consistency of cosmetic products, allowing for better spreadability and ease of application.

b. Film-Forming: When applied to the skin or hair, HPMC cellulose forms a protective film that helps to retain moisture, reducing water loss and maintaining hydration. It also enhances the longevity of cosmetic products on the skin or hair surface.

c. Suspending Agent: HPMC can suspend solid particles in cosmetic formulations, preventing their settling or sedimentation. This property is particularly useful in suspensions, scrubs, and exfoliating products.

• Construction Benefits:

a. Cement and Mortar Additive: HPMC acts as a thickener and water-retaining agent in cement-based products, such as mortars, tile adhesives, and renders. It improves workability, adhesion, and sag resistance, while reducing cracking and shrinkage.

b. Improved Open Time: Open time refers to the duration during which a construction material remains workable after application. HPMC extends the open time of adhesives, allowing for easier positioning and adjustment of tiles, wallpapers, and other materials.

c. Water Resistance: HPMC enhances the water resistance of construction materials, making them more durable and resistant to moisture-related damage. It improves the overall performance and lifespan of buildings and structures.

Overall, the hydroxypropyl methylcellulose benefits are vast and diverse. Its multifunctional properties make it an essential ingredient in a wide range of products, providing improved performance, stability, and user experience. As research and technology continue to advance, HPMC celluloseis likely to find even more applications in various industries, further demonstrating its value and versatility.

El proceso de fabricación de hidroxipropil metilcelulosa (HPMC) implica varios pasos para modificar la celulosa, un polímero natural derivado de fuentes vegetales. El proceso incluye tratamiento químico y reacción para introducir grupos hidroxipropilo y metilo en la columna vertebral de celulosa. Vamos a explorar el proceso de fabricación de HPMC en detalle.

• Extracción de celulosa:

El proceso comienza con la extracción de celulosa de fuentes vegetales. Las fuentes comunes incluyen pulpa de madera, algodón u otros materiales vegetales fibrosos. La celulosa se obtiene típicamente a través de una serie de tratamientos mecánicos y químicos, que implican descomponer el material vegetal y eliminar las impurezas para obtener un material de celulosa purificado.

• Tratamiento Álcali:

Una vez que se extrae la celulosa, se somete a un tratamiento alcalino para eliminar los componentes de hemicelulosa y lignina. Este tratamiento implica la inmersión de celulosa en una solución alcalina, tal como hidróxido de sodio (NaOH), para descomponer los materiales no celulósicos. El resultado es Celulosa purificada con un mayor grado de pureza.

• Etherificación:

El siguiente paso es el proceso de eterificación, donde los grupos hidroxipropilo y metilo se introducen en la columna vertebral de celulosa. Esto se logra a través de una serie de reacciones que involucran la celulosa y los reactivos apropiados.

A. Activación alcalina: La celulosa purificada se suspende en una solución alcalina, típicamente hidróxido de sodio, para activar la celulosa y hacerla más reactiva.

B. Hidroxipropilación: La celulosa activada se trata a continuación con óxido de propileno (PO) o un compuesto similar. El grupo hidroxipropilo del PO reacciona con los grupos hidroxilo de celulosa, lo que conduce a la Unión de grupos hidroxipropilo en la columna vertebral de celulosa.

C. Metilación: Después de la etapa de hidroxipropilación, la celulosa con grupos hidroxipropilo Unidos experimenta metilación. Esto implica la reacción de la celulosa hidroxipropilada con cloruro de metilo o un agente metilante similar. El grupo metilo del agente metilante reacciona con los grupos hidroxilo restantes en la celulosa, dando como resultado la introducción de grupos metilo en la estructura de celulosa.

• Neutralización y lavado:

Después del proceso de eterificación, la mezcla de reacción se neutraliza para detener reacciones adicionales y ajustar el pH. Se añaden soluciones ácidas o básicas para neutralizar cualquier exceso de álcali o ácido presente en la mezcla. A continuación, la mezcla neutralizada se lava a fondo para eliminar cualquier reactivo residual o subproducto, asegurando un producto HPMC purificado.

• Secado y fresado:

El paso final en el proceso de fabricación de HPMC implica secar y moler el producto HPMC obtenido. El producto se seca típicamente usando aire caliente o métodos de secado al vacío para eliminar la humedad y obtener un polvo seco. A continuación, el HPMC seco se muele para lograr el tamaño de partícula deseado y la uniformidad, lo que da como resultado un polvo fino listo para el envasado y la distribución.

Vale la pena señalar que el proceso de fabricación específico de HPMC puede variar ligeramente entre los diferentes fabricantes y sus métodos patentados. Sin embargo, los principios generales y los pasos involucrados en el proceso siguen siendo coherentes.

En conclusión, el proceso de fabricación de hidroxipropil metilcelulosa (HPMC) implica la extracción de celulosa de fuentes vegetales, seguido de tratamiento alcalino, activación alcalina, hidroxipropilación, metilación, neutralización, lavado, secado, y fresado. Este proceso da como resultado la producción de HPMC, un compuesto versátil con diversas aplicaciones en industrias como productos farmacéuticos, alimentos, cosméticos y construcción.